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The desktop client Outlook 2025 has not yet been announced final, so this is the guide for those testing the BETA version Open Outlook and click the Settings icon and then Manage for the email account you want to use with mySMTP
Outlook settings step 1
Outlook settings step 2
Type the Password for incoming email to enable account editing
Outlook password prompt
Outlook account editing enabled
Insert the marked information from your setup email or SMTP account.
Click Continue when done and wait for confirmation.
Outlook SMTP settings filled in

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Setup Guide for Outlook 2016-2025

Your account already uses IMAP for incoming mail. Follow the steps below to configure the outgoing SMTP server.

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1. Open Account Settings

Open Outlook and go to: File > Account Settings > Account Settings…

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2. Select Your Account

Select your existing email account (IMAP) and click Change…

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3. Outgoing Server Settings

In the Change Account window, set: Outgoing mail server: mail.smtp.dk Then click More Settings…

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4. Outgoing Server Tab

Open the Outgoing Server tab. Check: My outgoing server (SMTP) requires authentication Choose: Use same settings as my incoming mail server

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5. Advanced Tab

Open the Advanced tab and verify: Outgoing server (SMTP): 587 Encrypted connection: STARTTLS

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6. Test and Finish

Click Next to test your settings. When the test succeeds, click Close. Then click Finish to save the account settings.

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Outgoing SMTP Settings Summary